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SCIENTIFIC LITERATURE · MED

Comparison of the calcium-related factors in Parkinson's disease patients with healthy individuals.

Caspian J Intern Med · 2020-01-01

DOI: 10.22088/cjim.11.1.28PMID: 32042383

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

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BackgroundParkinson's disease (PD) is one of the most common neurodegenerative diseases (ND). Studies have demonstrated that biochemical markers have an association with PD. We aimed to investigate an association of biochemical markers including calcium, vitamin D, alkaline phosphatase (ALP), parathormone (PTH), and phosphorous with PD.MethodsThis study was conducted on 139 PD patients and 100 healthy individuals. Serum levels of calcium, phosphorous, ALP, PTH and vitamin D were evaluated. Furthermore, student's t-test and logistic regression models were used by SPSS.ResultsThe mean levels of calcium (9.4±0.7 and 9.0±0.8 ) and vitamin D (29.7±22.1 and 25.8±23.7) were higher in PD patients as compared with healthy controls, which only status of calcium being significantly different in the two groups (PConclusionResults show that mean levels of calcium are higher in PD patients relative to healthy controls. Thereby, higher levels of calcium may be associated with PD.

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