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SCIENTIFIC LITERATURE · MED

A versatile computational algorithm for time-series data analysis and machine-learning models.

NPJ Parkinsons Dis · 2021-11-09

DOI: 10.1038/s41531-021-00240-4PMID: 34753948

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

Here we introduce Local Topological Recurrence Analysis (LoTRA), a simple computational approach for analyzing time-series data. Its versatility is elucidated using simulated data, Parkinsonian gait, and in vivo brain dynamics. We also show that this algorithm can be used to build a remarkably simple machine-learning model capable of outperforming deep-learning models in detecting Parkinson's disease from a single digital handwriting test.

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