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BackgroundInflammatory bowel disease (IBD) may be associated with depression which is considered an important cause of dementia and Parkinson's disease (PD). In the present study, the effects of depression on the development of dementia and/or PD in patients with IBD were evaluated.Materials and methodsA nationwide population-based cohort study was conducted using claims data from the Health Insurance Review and Assessment Service in Korea. The incidence of dementia and PD were analyzed based on the presence of depression in patients with IBD.ResultsDuring a mean follow-up of 8 years, IBD patients with depression experienced dementia (6.7 vs. 2.0%; p p p p = 0.033; 2.13, p p p = 0.470; 2.75, p ConclusionThe risk of dementia and/or PD increased after a diagnosis of depression in patients with IBD.
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