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SCIENTIFIC LITERATURE · MED

Rectal Administration of Carbidopa/Levodopa.

Ochsner J · 2025-01-01

DOI: 10.31486/toj.24.0103PMID: 40538607

Open accessJournal Article; Case Reports; case-reportOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

BackgroundCarbidopa/levodopa is a vital medication administered to patients with Parkinson disease. In some clinical situations, oral administration of the medication is not feasible, so alternative routes for medication delivery must be explored to prevent severe complications.Case reportA 90-year-old male with Parkinson disease presented from a nursing home with worsening confusion and agitation. Because of the patient's condition and the inability to obtain enteric access, carbidopa/levodopa was administered rectally, resulting in an observed reduction of the patient's Parkinson symptoms.ConclusionWhen patients with Parkinson disease cannot take their medications orally, rectal administration of carbidopa/levodopa may be a reasonable and effective alternative route of administration.

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