NeuralCipher Research overview
The text below is the source article’s original abstract under a verified reuse license. cc by
BackgroundThe association between freezing of gait and motor function in Parkinson's disease is variable, and the results suggest the existence of subtypes.ObjectivesThis study aimed to identify the subtypes of freezing of gait and motor function in patients with Parkinson's disease.MethodsSixty-one patients were included. This study assessed motor function using the freezing of gait questionnaire, the Unified Parkinson's Disease Rating Scale Part III. For statistical analyses, we conducted a cluster analysis using the freezing of gait and motor function. Analysis of covariance with age and L-dopa dosing as a covariate was performed for each cluster (P ResultsCluster 1 (N = 15) had the lowest freezing of gait scores compared to the other clusters, and its motor function scores were lower than those of cluster 3 (N = 9) (P 0.05). Cluster 3 had moderate freezing of gait scores (vs. cluster 1, P 0.05) and higher motor function scores than the other clusters (P 0.05).ConclusionsThis study revealed new subtypes that presents with freezing of gait but high motor function in patients with Parkinson's disease.
Scientific assessment
Research question
Assess the question within the original study’s scope.
Methods & sample
Check the source article for study design and sample details.
Key findings
An editorially approved findings summary is not yet published for this record.
Limitations
Generalizability, bias and clinical meaning require separate assessment.
Methods, samples and clinical conclusions are not inferred from bibliographic metadata.