SCIENTIFIC LITERATURE · MED

Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort.

Krauss J, Upadhyay N, Purrer V, Borger V, Daamen M, Weiland H, Maurer A, Schmeel C, Radbruch A, Essler M, Wüllner U, Boecker H.

Mov Disord · 2025-08-08

DOI: 10.1002/mds.70003PMID: 40778498

Open accessLetterOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).

Scientific assessment

Research question

Assess the question within the original study’s scope.

Methods & sample

Check the source article for study design and sample details.

Key findings

An editorially approved findings summary is not yet published for this record.

Limitations

Generalizability, bias and clinical meaning require separate assessment.

Methods, samples and clinical conclusions are not inferred from bibliographic metadata.