NeuralCipher Research overview
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BackgroundParkinson's disease (PD) is an increasingly common comorbidity in patients undergoing total knee arthroplasty (TKA), yet its impact on readmissions remains poorly defined.MethodsUsing the Nationwide Readmissions Database 2020-2022, we identified elective, primary TKA cases. Patients with oncologic diagnoses, COVID-19-related admissions, acute fractures, and contralateral knee arthroplasty were excluded. Only the first readmission within 90 days was analyzed. Propensity score matching (1:1) was performed for demographics, comorbidities, hospital factors, and primary payer. The primary outcome was 90-day readmission. Secondary outcomes included infection-related readmissions, surgical procedures during readmission, readmission length of stay, readmission costs, and in-hospital mortality.ResultsAfter matching, 7286 patients were included (3675 PD vs 3611 non-PD). PD patients had a significantly higher 90-day readmission rate (13.0% vs 7.3%; P P P P P P ConclusionsPD is associated with a significantly higher risk of 90-day readmission following TKA, with readmissions frequently involving infection-related complications and surgical intervention. These findings highlight the importance of tailored perioperative care and enhanced postdischarge monitoring in this vulnerable population.Levels of evidenceLevel III.
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