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Four weeks of supervised home-based aerobic cycling improves cardiopulmonary function in patients with Parkinson's disease.

Front Neurol · 2026-03-13

DOI: 10.3389/fneur.2026.1761398PMID: 41908277

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

ObjectiveTo investigate the effects of a short-term, supervised home-based aerobic cycling intervention on cardiopulmonary function in patients with mild-to-moderate PD.DesignA single-center, pre-post intervention study was conducted. Seventeen PD patients (Hoehn-Yahr stage 1-3) underwent a 4-week supervised home-based cycling program, exercising at 70-80% of heart rate reserve for 40 min per session, three times per week. Remote supervision was facilitated via a mobile application. The primary outcome was maximal power output (W). Secondary outcomes included anaerobic threshold (AT), peak oxygen uptake (VO₂peak), heart rate parameters, and pulmonary function tests. Assessments were performed at baseline and after the intervention in the ON medication state.ResultsAfter the 4-week intervention, key cardiopulmonary parameters showed significant increases in Maximal power output (p p = 0.006). Anaerobic threshold power and related heart rate measures also showed significant enhancement (p p ConclusionA 4-week supervised home-based aerobic cycling program is a feasible and effective intervention, leading to significant improvements in aerobic capacity, metabolic efficiency, and cardiovascular response in patients with mild-to-moderate PD.

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