NeuralCipher Research overview
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Precise intraoperative localisation of subcortical brain structures remains a critical challenge in deep brain stimulation, yet openly available microelectrode recording datasets are scarce. We present a dataset of 6,646 processed MER recordings from 132 patients with neurological disorders, including Parkinson's disease, dystonia, Huntington's disease, epilepsy and others, acquired during DBS procedures. Signals were band-pass filtered and cleaned using an automated machine learning-based artifact rejection pipeline; annotation quality was confirmed by independent review. In addition an experienced electrophysiologist annotated representative examples of three basal ganglia structures encountered along the electrode trajectories: striatum/putamen, external globus pallidus (GPe), and internal globus pallidus (GPi). The dataset, released together with the full processing pipeline and metadata, is intended to support semi-supervised subcortical structure classification, pathological neuronal activity analysis, and the development of novel DBS targeting methods.
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