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SCIENTIFIC LITERATURE · MED

Procerus sign as a diagnostic clue for progressive supranuclear palsy.

Arq Neuropsiquiatr · 2026-05-01

DOI: 10.1055/s-0046-1824436PMID: 42336349

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

AbstractThe procerus sign is associated with some diseases that initially manifest as atypical parkinsonism, especially progressive supranuclear palsy (PSP). It is described as a vertical contraction of the muscles in the glabellar region. This sign helps to clinically differentiate atypical parkinsonism diseases, especially in the early stages, when many conditions are similar, in terms of clinical presentation and poor response to levodopa. Thus, the procerus sign can be an important clue in the suspicion of PSP.

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