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Home-based deep sleep modulation in Parkinson's disease: extension study on long-term feasibility and sleep-related outcomes.

NPJ Parkinsons Dis · 2026-07-10

DOI: 10.1038/s41531-026-01461-1PMID: 42431926

Open accessbrief-report; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

This study assessed feasibility and effects of a randomised two-week, at-home intervention with phase-targeted auditory stimulation (PTAS) of slow waves in Parkinson's disease (PD). We reproduced previously reported enhancement of slow wave activity and confirmed indications of improved patient-reported outcomes. Together with the high adherence and data quality, this suggests that home-based PTAS protocols are a feasible method for investigating the long-term therapeutic potential of deep sleep enhancement in PD.

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