SCIENTIFIC HUB

Follow the evidence.

SCIENTIFIC LITERATURE · PPR

Non-Motor Symptoms: The Hidden Face of Parkinson’s Disease

· 2025-11-10

DOI: 10.20944/preprints202511.0689.v1

Check source for accessPreprintOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

Non-motor symptoms (NMS) of Parkinson's disease (PD) were recognized by James Parkinson himself about 200 years ago and are now considered to be an integral part of PD, significantly contributing to the worse of patients’ quality of life. Although awareness of NMS is growing, and several scientific societies have now dedicated non-motor study groups, the NMS burden is still the hidden face of PD and in most cases the clinicians’ views are focused on the motor symptoms alone. Literature research has been performed using several databases and scientific journals; this review provides a comprehensive description of the most common NMS in PD, their clinical phenotype, social impact, diagnosis, and therapeutic management. Early recognition of these features may lead to more prompt and effective treatment and may help to better understand patients’ needs.

Scientific assessment

01

Research question

Assess the question within the original study’s scope.

02

Methods & sample

Check the source article for study design and sample details.

03

Key findings

An editorially approved findings summary is not yet published for this record.

04

Limitations

Generalizability, bias and clinical meaning require separate assessment.

Methods, samples and clinical conclusions are not inferred from bibliographic metadata.