Statins as Neuroinflammatory Therapy, Bibliometric Study

Research overview

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Introduction: Neuroinflammase, a key mechanism in neurodegenerative diseases like Alzheimer and Parkinson, is influenced by statin, a lipid-binding protein. Studies show that statin can mitigate the likelihood of developing dementia and Alzheimer’s disease and can also reduce leukocytosis and T-regulatory function. Nevertheless, there is restricted literature on the use of statin in neuroinflammation. The objective of this investigation is to conduct a bibliometric analysis of statin use in neuroinflammation, providing valuable insights into research development and future research questions. Methods In this work, a literature review methodology is employed to gather data from the Scopus database using the keywords neuroinflammation and statins. Data were analyzed using Biblioshiny and VOSviewer software to produce visualizations and bibliometric maps. We conducted quantitative and qualitative analysis. Results The research trend found are Documents by Year, Most Global Cited Document, Most Relevant Sources, Factorial Map Of The Documents With The Highest Contributes, Documents by Author, Most Relevant Affiliations, Documents by Subject Area, Trend Topic, Network Visualization, Overlay visualization of scopus, database using Vosviewer, Density Visualization, Thematic Map, Thematic Evolution, Cluster Analysis, Qualitative Analysis, and Word Cloud. Conclusions The study highlights the potential for further research on statins and neuroinflammation, aiming to better understand their role in treating neuroinflammation and enhance the quality of life for patients with neuroinflammatory conditions.

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