Teşhisi geciktiren Parkinson hastalığı özelliklerini ortaya çıkarmak için öngörüsel modelleme.

Araştırma özeti

Aşağıdaki metin kaynak makalenin lisansı doğrulanmış orijinal özetidir. cc by

PD patients present with diverse symptoms, complicating timely diagnosis. We analyzed 1124 PD trajectories using a novel model-based approach to estimate whether diagnosis was early or late compared to cohort averages. Higher age, specific non-motor symptoms, and fast disease progression were linked to later diagnosis, while gait impairment led to earlier diagnosis. Our findings are in line with a biological definition of PD that extends beyond classical motor symptoms.

İlgili konular