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LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model.

Blasco-Agell L, Pons-Espinal M, Testa V, Roch G, Montero-Muñoz J, Fernandez-Carasa I, Baruffi V, Gonzalez-Sepulveda M, Richaud-Patin Y, Jimenez S, Cuadros T, Cladera-Sastre JM, Compte J, Manglano-Artuñedo Z, Ventura S, Juan M, Tolosa E, Raya A, Vila M, Consiglio A.

Commun Biol · 2025-08-12

DOI: 10.1038/s42003-025-08544-4PMID: 40796643

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons.

Gorgogietas V, Weiss A, Cousin L, Hoffmann D, Schmitt K, Ogier A, Barbuti PA, Santos BFR, Boussaad I, Wittich A, Zaliani A, Pless O, Krüger R, Sommer P, Wilbertz JH.

Sci Rep · 2025-08-12

DOI: 10.1038/s41598-025-14735-0PMID: 40796766

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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