191.030 articles found

Optimizing Parkinson’s Disease progression scales using computational methods

Benesh A, Alcalay RN, Mirelman A, Shamir R.

· 2025-08-01

DOI: 10.1101/2025.07.31.25332494

Sex-specific vulnerability to behavioural and morphological alterations in a mouse model of Parkinson’s disease overexpressing mutant A53T alpha-synuclein

Zubelzu M, Bidgood R, Murueta-Goyena A, Ruiz-Ortega J, Lafuente J, Morera-Herreras T.

· 2025-08-01

DOI: 10.1101/2025.07.30.667616

Elevated phosphorylated α-synuclein and phosphorylated tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis

Lunn MO, Thakur K, Thakur K, Lengacher NA, Hake-Volling Q, aSCENT-PD Investigators, Tomlinson JJ, Sad S, Brown EG, Schlossmacher MG.

· 2025-08-01

DOI: 10.1101/2025.07.31.667659

Long-acting injectable delivery system comprising ordered mixed drug aggregates with deaggregating and uniformly embeddable viscoelastic -polysaccharide solutions

Park JS, Lee DG, Myung JH, Jeong MY, Yang IG, Lee GY, Yeo JW, Park CW, Kim JH, Shin YB, Ho MJ, Jin SG, Choi YS, Kang MJ.

Carbohydrate Polymers. · 2025-08-01

cis and trans isomers of phospho-tau proteins differently affect amyloid aggregation

Hajipour MJ, Rezvantalab S, Mohammad-Beigi H, Maleki R, Ghezelbashan G, Alyami EM, Ramamoorthy A, Maurizi L.

International Journal of Biological Macromolecules · 2025-08-01

GLP1 secretagogue cinnamaldehyde upregulates GLP1/PI3K/AKT and Nrf2 pathways to exert neuroprotection in a rotenone induced mouse model of Parkinson's disease

Mathur K, Soni R, Yadav R, Patel BD, Shah J.

International Journal of Biological Macromolecules · 2025-08-01

Akkermansia muciniphila Akk11 Supplementation Attenuates MPTP-Induced Neurodegeneration by Inhibiting Microglial NLRP3 Inflammasome

Wang W, Shi S, Su M, Li Y, Yao X, Jiang J, Yao W, Qin X, Wang Z, Tang C.

Probiotics & Antimicro. Prot · 2025-08-01

Exploring the reactivity of 5,5-dimethyl-1,2-oxathiolan-4-one 2,2-dioxide and their spirocyclopropyl counterpart

Poliudov AO, Havryshko DY, Krasilov DI, Sorokin MD, Milokhov DS, Virych PA, Virych PA, Omelian ТV, Kysil AI, Dobrydnev AV.

Tetrahedron · 2025-08-01

Screening ligands interacting with NDUFS3 from Oroxylum indicum extract using bioaffinity ultrafiltration combined with in vitro protein purification

Ma Yf, Zhang Xx, Kong Dz, Li Dq.

Biochemical and Biophysical Research Communications · 2025-08-01

Sulfated polysaccharides of Caulerpa cupressoides var. flabellata: An investigation into their antioxidant properties and biocompatibility

Farias PFF, Rodrigues VM, de Souza AM, Oliveira DD, Luchiari AC, Rocha HAO, Moreira SMG.

J Appl Phycol · 2025-08-01

Challenges in studying air pollution to neurodegenerative diseases

Kwon D, Paul KC, O'Sharkey K, Paik SA, Youyou, Bronstein JM, Ritz B.

Environmental Research · 2025-08-01

Therapeutic potential of lipids of Irish marine cyanobacteria Chlorogloea microcystoides SABC 022904 and Phormidium africanum SABC 022001

Shiels K, Silva J, Alves C, Pedrosa R, Murray P, Saha SK.

Journal of functional foods · 2025-08-01