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15.286 articles found

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PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinson’s disease

Chiang CY, Pratuseviciute N, Lin Y, Adhikari A, Yeshaw WM, Flitton C, Sherpa PL, Tonelli F, Rektorova I, Lynch T, Siuda J, Rudzińska-Bar M, Pulyk O, Bauer P, Beetz C, Dickson DW, Ross OA, Wszolek ZK, Klein C, Zimprich A, Alessi DR, Sammler EM, Pfeffer SR.

· 2025-03-19

DOI: 10.1101/2025.03.19.644182

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance.

Duplan E, Bernardin A, Goiran T, Leroudier N, Casimiro M, Pestell R, Tanaka S, Malleval C, Honnorat J, Idbaih A, Martin L, Castel H, Checler F, Alves da Costa C.

Cell Death Dis · 2025-03-19

DOI: 10.1038/s41419-025-07509-zPMID: 40108111

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Overexpression of α–synuclein in Midbrain Dopamine Neurons Reduces Dopamine Release Without Cell Loss and Drives Mild Motor Deficits in Mice

Barcomb K, Hsiao JT, Lemak J, Zhuang X, Coutant B, Yanez A, Behal A, Fu Y, Lerner T, Nakamura K, Edwards R, Khaliq Z, Halliday G, Ford C, Nelson AB.

· 2025-03-18

DOI: 10.1101/2025.03.17.643840

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer's disease.

Franzmeier N, Roemer-Cassiano SN, Bernhardt AM, Dehsarvi A, Dewenter A, Steward A, Biel D, Frontzkowski L, Zhu Z, Gnörich J, Pescoller J, Wagner F, Hirsch F, de Bruin H, Ossenkoppele R, Palleis C, Strübing F, Schöll M, Levin J, Brendel M, Höglinger GU.

Mol Neurodegener · 2025-03-18

DOI: 10.1186/s13024-025-00822-3PMID: 40098057

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Apigenin enhances Nrf2-induced chaperone-mediated autophagy and mitigates α-synuclein pathology: Implications for Parkinson's disease therapy.

Huang YB, Tian LL, Zhu ZW, Zhou KG, Lai X, Peng YZ, Wu Z, Tong WF, Wang H, Wang XJ, Guan Q, Jin LJ, Feng Y, Weng WY, Zhang JX.

Phytomedicine · 2025-03-17

DOI: 10.1016/j.phymed.2025.156652PMID: 40215824

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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