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NERINE reveals rare variant associations in gene networks across phenotypes and implicates an <i>SNCA-PRL-LRRK2</i> subnetwork in Parkinson’s disease

Nazeen S, Wang X, Morrow AR, Strom R, Ethier E, Ritter D, Henderson ABH, Afroz J, Cassa CS, Stitziel NO, Gupta RM, Luk KC, Studer L, Khurana V, Sunyaev SR.

· 2025-01-10

DOI: 10.1101/2025.01.07.631688

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Microglia depletion reduces neurodegeneration and remodels extracellular matrix in a mouse Parkinson's disease model triggered by α-synuclein overexpression.

Zhang Z, Niu K, Huang T, Guo J, Xarbat G, Gong X, Gao Y, Liu F, Cheng S, Su W, Yang F, Liu Z, Ginhoux F, Zhang T.

NPJ Parkinsons Dis · 2025-01-09

DOI: 10.1038/s41531-024-00846-4PMID: 39779738

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1.

Mettu A, Glavatskikh M, Wang X, Lara Ordóñez AJ, Li F, Chau I, Ackloo S, Arrowsmith C, Bolotokova A, Ghiabi P, Gibson E, Halabelian L, Houliston S, Harding RJ, Hutchinson A, Loppnau P, Perveen S, Seitova A, Zeng H, Schapira M, Taymans JM, Kireev D.

Chem Sci · 2025-01-09

DOI: 10.1039/d4sc07532cPMID: 39877816

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

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