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“Parkinson LRRK2” Clear search

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Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.

Williamson MG, Madureira M, McGuinness W, Heon-Roberts R, Mock ED, Naidoo K, Cramb KML, Caiazza MC, Malpartida AB, Lavelle M, Savory K, Humble SW, Patterson R, Davis JB, Connor-Robson N, Ryan BJ, Wade-Martins R.

Hum Mol Genet · 2023-09-01

DOI: 10.1093/hmg/ddad102PMID: 37384414

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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LRRK2 exonic variants are associated with lysosomal hydrolase activities and lysosphingolipid alterations in Parkinson's disease.

Usenko TS, Senkevich KA, Basharova KS, Bezrukova AI, Baydakova GV, Tyurin AA, Beletskaya MV, Kulabukhova DG, Grunina MN, Emelyanov AK, Miliukhina IV, Timofeeva AA, Zakharova EY, Pchelina SN.

Gene · 2023-07-18

DOI: 10.1016/j.gene.2023.147639PMID: 37473971

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease.

Phillips B, Western D, Wang L, Timsina J, Sun Y, Gorijala P, Yang C, Do A, Nykänen NP, Alvarez I, Aguilar M, Pastor P, Morris JC, Schindler SE, Fagan AM, Puerta R, García-González P, de Rojas I, Marquié M, Boada M, Ruiz A, Perlmutter JS, Dominantly Inherited Alzheimer Network (DIAN) Consortia, Ibanez L, Perrin RJ, Sung YJ, Cruchaga C.

NPJ Parkinsons Dis · 2023-07-08

DOI: 10.1038/s41531-023-00555-4PMID: 37422510

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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