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De novo Design of Polymorph-Specific Binders Targeting α-Synuclein Fibrils

Sadek A, Rey NL, Kunka A, Harteveld Z, Georgeon S, Schmidt J, Buell AK, Melki R, Lashuel HA, Correia BE.

· 2026-06-16

DOI: 10.64898/2026.06.13.732066

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Genetic and epigenetic complexity of Parkinson's disease: From dopamine pathways to estrogen interplay.

Deena K, Nathish L, Fenwick EA, Karthi M, Sivasamy R.

Int Rev Neurobiol · 2026-06-16

DOI: 10.1016/bs.irn.2026.05.021PMID: 42442910

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Glial control of extracellular α-synuclein propagation in LRRK2 Parkinson's disease.

Datta I, Sahu DD.

Adv Immunol · 2026-06-16

DOI: 10.1016/bs.ai.2026.04.005PMID: 42629126

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Open access

The Prodromal Synucleinopathy Rating Scale: An Assessment in Patients With REM Sleep Behavior Disorder.

Boeve BF, Nie Y, Lu R, De La Cruz H, Avidan AY, Bliwise DL, Campbell MC, Criswell SR, Davis AA, Duff K, Elliott J, Ferman TJ, Fields JA, Forsberg LK, Gagnon JF, Howell M, Huddleston DE, Lim MM, Locke J, McCarter SJ, McLeland J, Miglis MG, Miyagawa T, Neilson LE, Nichols K, Pelletier A, Schenck CH, Louis EKS, Sum-Ping O, Trotti LM, Videnovic A, Xiong C, Postuma R, Ju YS, NAPS Consortium.

Neurology · 2026-06-16

DOI: 10.1212/wnl.0000000000218176PMID: 42302227

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Open access

Deep brain stimulation in alpha-synuclein models of Parkinson's disease: Bridging the translational gap.

Kondrataviciute L, Weber H, Kapadia M, Aguirre-Padilla DH, Fauser M, Valiante TA, Hutchison WD, Milosevic L, Storch A, Kalia LV, Kalia SK.

J Parkinsons Dis · 2026-06-16

DOI: 10.1177/1877718x261459876PMID: 42299658

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LRRK2/LRRK1 interactions modulate Rab7 activity and inhibit lysosomal exocytosis

Merghani M, Gerhardt E, Hesse M, Fahlbusch C, Böcker CA, Outeiro TF.

· 2026-06-15

DOI: 10.64898/2026.06.12.731951

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Open access

Biomarkers stewardship in parkinsonism: integrating alpha-synuclein seed amplification assays and neurofilament light chain into diagnostic pathways and patient communication.

Leclercq V.

J Neurol · 2026-06-15

DOI: 10.1007/s00415-026-13933-8PMID: 42295486

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An automated workflow for quantifying the formation of synuclein aggregates in human dopaminergic neurons.

Han C, Nguyen-Renou E, Benaliouad F, Luo W, Chen CX, Alluli A, Villegas L, Beitel LK, Shlaifer I, Reintsch WE, Krahn AI, Cid Pellitero ED, Fon EA, Durcan TM.

Methods · 2026-06-15

DOI: 10.1016/j.ymeth.2026.06.005PMID: 42297199

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Open access

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease.

Ji Y, Lu L, Chen K, Zhang R, Lu Y, Shi Y, Fang X.

Neuroprotection · 2026-06-14

DOI: 10.1002/nep3.70040PMID: 42499343

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Beyond RSWA in prodromal α-synuclein disease: Do periodic limb movements signal potential early dopaminergic dysfunction?

Gorantla S, Cesari M, Ferri R.

Sleep Med · 2026-06-13

DOI: 10.1016/j.sleep.2026.109086PMID: 42308678

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Structural insight into binding of novel PET tracer MODAG-005 to lipidic 𝛼-Synuclein fibrils

Griesinger C, Kim M, Matthes D, Frieg B, Leonov A, Ryazanov S, Bleher D, Grotegerd A, Dienemann C, Giese A, Schroeder G, Becker S, Herfert K, de Groot B, Andreas L.

· 2026-06-12

DOI: 10.21203/rs.3.rs-9415794/v1

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Treadmill exercise rescues motor deficits in parkinsonian mice by modulating striatal D2-MSN activity: evidence from calcium imaging and chemogenetics.

Chen P, Zeng Y, Liu B, Yang Q, Xue WC, Liu N, Zhuang C.

Front Syst Neurosci · 2026-06-12

DOI: 10.3389/fnsys.2026.1851618PMID: 42368410

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Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

14.570 articles found

De novo Design of Polymorph-Specific Binders Targeting α-Synuclein Fibrils

Genetic and epigenetic complexity of Parkinson's disease: From dopamine pathways to estrogen interplay.

Glial control of extracellular α-synuclein propagation in LRRK2 Parkinson's disease.

The Prodromal Synucleinopathy Rating Scale: An Assessment in Patients With REM Sleep Behavior Disorder.

Deep brain stimulation in alpha-synuclein models of Parkinson's disease: Bridging the translational gap.

LRRK2/LRRK1 interactions modulate Rab7 activity and inhibit lysosomal exocytosis

Biomarkers stewardship in parkinsonism: integrating alpha-synuclein seed amplification assays and neurofilament light chain into diagnostic pathways and patient communication.

An automated workflow for quantifying the formation of synuclein aggregates in human dopaminergic neurons.

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease.

Beyond RSWA in prodromal α-synuclein disease: Do periodic limb movements signal potential early dopaminergic dysfunction?

Structural insight into binding of novel PET tracer MODAG-005 to lipidic 𝛼-Synuclein fibrils

Treadmill exercise rescues motor deficits in parkinsonian mice by modulating striatal D2-MSN activity: evidence from calcium imaging and chemogenetics.

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