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Distinct metabolomic and proteomic signatures in Parkinson's disease patients with REM sleep behavior disorder.

Shao Y, Wang J, Liu Y, Ni Y, Liu Z, Li Y, Jia Q, Li Q, Wang X, Li T, Liu M, Zhang S, Guo Y, Guo X, Wang D, Liu Y, Liu C, Cai H, Ning Y, Zhang J, Xu G, Le W.

Signal Transduct Target Ther · 2026-03-30

DOI: 10.1038/s41392-026-02613-8PMID: 41912482

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Semi-Automated Neuromelanin-Sensitive MRI Reveals Substantia Nigra Volume Reduction in Early Parkinson's Disease with Moderate Diagnostic Performance.

Silovs A, Skuburs GK, Zdanovskis N, Sevcenko A, Mednieks J, Naudins E, Bartusevica S, Umbrasko S, Zarina L, Zelge L, Pastare AA, Steinberga J, Skilters J, Pinna B, Platkajis A.

Diagnostics (Basel) · 2026-03-30

DOI: 10.3390/diagnostics16071046PMID: 41975757

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Polyfunctionalized <i>N</i>-Arylsulfonyl Indoles: Identification of (<i>E</i>)-<i>N</i>-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1<i>H</i>-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-Based Therapy of Parkinson's Disease.

Toledano-Pinedo M, Porro-Pérez A, Schäker-Hübner L, Diez-Iriepa D, Iriepa I, Siwek A, Wolak M, Satała G, Bojarski AJ, Doroz-Płonka A, Handzlik J, Godyń J, Dallemagne P, Rochais C, Davis A, Since M, Pérez B, Bellver-Sanchis A, Irisarri A, Pallàs M, Solana-Manrique C, López-Muñoz F, Ismaili L, Griñán-Ferré C, Paricio N, Hansen FK, Więckowska A, Marco-Contelles J.

Int J Mol Sci · 2026-03-30

DOI: 10.3390/ijms27073135PMID: 41977320

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
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Lack of Cerebrospinal Fluid α-Synuclein Seeding in VPS35 D620N- and LRRK2 Y1699C-Linked Parkinson's Disease.

Santinelli L, Pratuseviciute N, Lange LM, Kleinz T, Brüggemann N, Streubel-Gallasch L, Möller M, Zimprich A, Brücke C, Good JM, Griebner N, Padmanabhan S, Seibler P, Bauer P, Vandenberghe W, Sammler E, Blauwendraat C, Klein C, Borsche M.

Mov Disord · 2026-03-30

DOI: 10.1002/mds.70291PMID: 41912440

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

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