SCIENTIFIC HUB

Follow the evidence.

14.777 articles found

Source record

A new therapeutic approach for Parkinson’s disease: dual targeting of α-Synuclein aggregation and microglial function by the novel immunomodulator 3-Monothiopomalidomide

Palmas MF, Aminzadeh K, Runfola M, Parekh P, Porcedda C, Tweedie D, Casula L, Cardia MC, Marongiu J, Etzi M, Lai F, Serra M, Pisanu A, Sogos V, De Simone A, Kim DS, Greig NH, Carta AR.

· 2026-03-30

DOI: 10.64898/2026.03.26.714051

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Polyfunctionalized <i>N</i>-Arylsulfonyl Indoles: Identification of (<i>E</i>)-<i>N</i>-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1<i>H</i>-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-Based Therapy of Parkinson's Disease.

Toledano-Pinedo M, Porro-Pérez A, Schäker-Hübner L, Diez-Iriepa D, Iriepa I, Siwek A, Wolak M, Satała G, Bojarski AJ, Doroz-Płonka A, Handzlik J, Godyń J, Dallemagne P, Rochais C, Davis A, Since M, Pérez B, Bellver-Sanchis A, Irisarri A, Pallàs M, Solana-Manrique C, López-Muñoz F, Ismaili L, Griñán-Ferré C, Paricio N, Hansen FK, Więckowska A, Marco-Contelles J.

Int J Mol Sci · 2026-03-30

DOI: 10.3390/ijms27073135PMID: 41977320

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Cytotoxic T cell recognition of α-synuclein drives pathogenic immune responses in multiple system atrophy.

Moon JS, Moutusy SI, Zhang M, Ndayisaba A, Rodriguez D, El Kodsi DN, Kuzkina A, Younis S, Jahanbani S, Dam LSV, Courtney Y, Netanel A, Sharpe O, Miglis MG, Steinman L, Khurana V, Jahanbani F, Robinson WH.

Proc Natl Acad Sci U S A · 2026-03-30

DOI: 10.1073/pnas.2537271123PMID: 41911451

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

Lack of Cerebrospinal Fluid α-Synuclein Seeding in VPS35 D620N- and LRRK2 Y1699C-Linked Parkinson's Disease.

Santinelli L, Pratuseviciute N, Lange LM, Kleinz T, Brüggemann N, Streubel-Gallasch L, Möller M, Zimprich A, Brücke C, Good JM, Griebner N, Padmanabhan S, Seibler P, Bauer P, Vandenberghe W, Sammler E, Blauwendraat C, Klein C, Borsche M.

Mov Disord · 2026-03-30

DOI: 10.1002/mds.70291PMID: 41912440

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Source record

Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson's Disease.

Yu EC, Zhou H, Yan X, Logan KM, Li D, Gulati A, Poremba KE, Ardolino MJ, Su J, Xiao D, Palte RL, McMinn SE, Nogle LM, Adpressa DA, Burgess SA, Xiong T, Otte KM, Chobanian HR, Bass A, Lee S, Pearson K, Messina E, Parisi M, Barnum J, Sobol Z, Ciaccio PJ, DiMauro EF, Fell MJ, Fuller PH.

J Med Chem · 2026-03-29

DOI: 10.1021/acs.jmedchem.6c00238PMID: 41906303

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Source record

Bridging Genetics and Precision Medicine in Parkinson’s Disease through GP2

Atterling Brolin K, Lange LM, Navarro-Jones E, Jasaityte S, Ye Beh Y, Fang Z, Iwaki H, Jones L, Klein C, Kleinz T, Leonard HL, Mata IF, Noyce AJ, Okubadejo N, Saffie Awad P, Screven L, Tan AH, Toffoli M, Vitale D, Singleton A, Blauwendraat C, Nalls M, Morris HR, the Global Parkinson’s Genetics Program (GP2).

· 2026-03-28

DOI: 10.64898/2026.03.26.26349418

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.
Open access

The genetic spectrum of LRRK2 variants in Parkinson's disease: findings from a large Chinese cohort.

Wan J, Pan H, Chang D, Zhao Y, Xu Q, Yao L, Sun Q, Zhang X, He R, Wang C, Zhang H, Lei L, Wang Y, Li M, Wu H, Ma J, Wu Y, Xu Y, Xiong N, Wang T, Wang X, Chen L, Xu Y, Cao H, Zhang K, Liu W, Zhang Y, Mao C, Wang Q, Xue Z, Zhang Z, Cheng O, Huang W, Zhao G, Cui G, Chen T, Wang P, Di W, Liu H, Zheng H, Chen C, Guo H, Xia K, Zhang Z, Yuan K, Li J, Wang J, Guo J, Shen L, Jiang H, Liu C, Liu J, Chan P, Liu Z, Tang B, Parkinson’s Disease & Movement Disorders Multicenter Database and Collaborative Network in China (PD-MDCNC), China Essential Tremor Alliance (CETA).

NPJ Parkinsons Dis · 2026-03-28

DOI: 10.1038/s41531-026-01315-wPMID: 41904258

A bibliographic record traceable to Europe PMC. Türkçe başlık: makine çevirisi, editoryal kontrol bekliyor.

Records come from scientific sources. Bibliographic counts do not represent completed translations or editorial approvals.

Filters

Filters

Clear
Publication year
Research area
Author
Journal
Publication type
Source & language
Open accessAccess does not establish reuse rights.