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SCIENTIFIC LITERATURE · MED

Tumours and tremors: how PTEN regulation underlies both.

Br J Cancer · 2006-03-01

DOI: 10.1038/sj.bjc.6602994PMID: 16495927

Open accessResearch Support, Non-U.S. Gov't; review-article; Review; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

Mutations of the tumour suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) are seen in many human cancers. However, dysregulation of PTEN may be involved in other disease states such as Parkinson's disease. This minireview describes recent work examining PTEN regulation and its implications for the development of both cancer and neurodegenerative disease.

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