Reading Parkinson systematic reviews and meta-analyses

Parkinson’s disease Digital biomarkers Genetics & alpha-synuclein Treatment research Movement disorders Neuroimaging Clinical research Systematic reviews

RESEARCH GUIDE

Find the source. Evaluate the evidence.

This area groups records using publication titles and source-reported publication types. A thematic match is not clinical guidance or expert assessment. Always consult the original study for methods, sample sizes, findings and limitations.

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Reading Parkinson systematic reviews and meta-analyses

A systematic review and a meta-analysis describe different features of an evidence synthesis. Check the search strategy, final search date, eligibility criteria and characteristics of included studies. Research published after the search may not be included; the final search date helps establish this boundary.

For a meta-analysis, inspect which studies were combined, compatibility of outcome measures and differences between studies. Risk-of-bias assessment, sensitivity analyses and authors’ limitations are central to interpretation. Do not assume that one pooled numerical result has an identical meaning across all populations or clinical settings. Use publication-type filters to distinguish reviews from original research in this catalog.

From the literature

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Source record

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell · 2017-10-01

DOI: 10.1016/j.cell.2017.09.021PMID: 28985560

Article details

Source record

MDS clinical diagnostic criteria for Parkinson's disease.

Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G.

Mov Disord · 2015-10-01

DOI: 10.1002/mds.26424PMID: 26474316

Article details

Source record

Parkinson's disease.

Kalia LV, Lang AE.

Lancet · 2015-04-19

DOI: 10.1016/s0140-6736(14)61393-3PMID: 25904081

Article details

Source record

The Microbiota-Gut-Brain Axis.

Cryan JF, O'Riordan KJ, Cowan CSM, Sandhu KV, Bastiaanssen TFS, Boehme M, Codagnone MG, Cussotto S, Fulling C, Golubeva AV, Guzzetta KE, Jaggar M, Long-Smith CM, Lyte JM, Martin JA, Molinero-Perez A, Moloney G, Morelli E, Morillas E, O'Connor R, Cruz-Pereira JS, Peterson VL, Rea K, Ritz NL, Sherwin E, Spichak S, Teichman EM, van de Wouw M, Ventura-Silva AP, Wallace-Fitzsimons SE, Hyland N, Clarke G, Dinan TG.

Physiol Rev · 2019-10-01

DOI: 10.1152/physrev.00018.2018PMID: 31460832

Article details

Source record

Parkinson disease.

Poewe W, Seppi K, Tanner CM, Halliday GM, Brundin P, Volkmann J, Schrag AE, Lang AE.

Nat Rev Dis Primers · 2017-03-23

DOI: 10.1038/nrdp.2017.13PMID: 28332488

Article details

Open access

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

GBD 2016 Neurology Collaborators.

Lancet Neurol · 2019-03-14

DOI: 10.1016/s1474-4422(18)30499-xPMID: 30879893

Article details

Source record

Parkinson's disease.

Bloem BR, Okun MS, Klein C.

Lancet · 2021-04-10

DOI: 10.1016/s0140-6736(21)00218-xPMID: 33848468

Article details

Source record

Ageing as a risk factor for neurodegenerative disease.

Hou Y, Dan X, Babbar M, Wei Y, Hasselbalch SG, Croteau DL, Bohr VA.

Nat Rev Neurol · 2019-09-09

DOI: 10.1038/s41582-019-0244-7PMID: 31501588

Article details

When reading a study

Identify the publication type and research question.
Distinguish human, animal and laboratory research.
Assess results and uncertainty from the original text.
Check the source for retractions and corrections.