NeuralCipher Research overview
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BackgroundParkinson's Disease patients undergo time-consuming programming to refine stimulation parameters after deep brain stimulation surgery.ObjectiveTo assess whether the use of the advanced functions of a patient's programmer would facilitate programming of deep brain stimulation.MethodsThirty patients were randomly allocated to the use of advanced versus simple mode of the patient programmer in this single-centre, prospective, randomized, controlled study. Primary outcome was the number of days required to optimize the stimulation settings.ResultsThe number of days required to optimize stimulation was significantly lower in the simple mode (88.5 ± 33.1 vs. 142.1 ± 67.4, p = 0.01). In addition, the advanced mode group had a higher number of side effects (5.4 ± 3.1 vs. 2.6 ± 1.9, p = 0.0055).ConclusionsThe use of the advanced functions of patient programmer delays programming optimization and it is associated with a higher number of side effects. These findings highlight the need for other methods for faster and safer stimulation programming.
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