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SCIENTIFIC LITERATURE · MED

Neurodegenerative Diseases and Cholesterol: Seeing the Field Through the Players.

Front Aging Neurosci · 2021-11-03

DOI: 10.3389/fnagi.2021.766587PMID: 34803658

Open accessreview-article; Review; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

Neurodegenerative diseases, namely Alzheimer's (AD), Parkinson's (PD), and Huntington's disease (HD) together with amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), devastate millions of lives per year worldwide and impose an increasing socio-economic burden across nations. Consequently, these diseases occupy a considerable portion of biomedical research aiming to understand mechanisms of neurodegeneration and to develop efficient treatments. A potential culprit is cholesterol serving as an essential component of cellular membranes, as a cofactor of signaling pathways, and as a precursor for oxysterols and hormones. This article uncovers the workforce studying research on neurodegeneration and cholesterol using the TeamTree analysis. This new bibliometric approach reveals the history and dynamics of the teams and exposes key players based on citation-independent metrics. The team-centered view reveals the players on an important field of biomedical research.

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Methods, samples and clinical conclusions are not inferred from bibliographic metadata.