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SCIENTIFIC LITERATURE · MED

Lack of full sequencing GBA1 studies for patients with Parkinson's disease in Latin America.

NPJ Parkinsons Dis · 2022-08-08

DOI: 10.1038/s41531-022-00358-zPMID: 35941142

Open accessresearch-article; Journal ArticleOriginal source ↗

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The text below is the source article’s original abstract under a verified reuse license. cc by

Full sequencing of the GBA1 gene in patients with Parkinson's disease provides a wide screening of pathogenic variants, but less developed regions of the world, like Latin America, may have difficulties in performing full sequencing. We performed a systematic review with meta-analysis to explore the prevalence and the odds ratio of specific GBA1 variants in Parkinson's disease in Latin America. We noted a lack of full sequencing GBA1 studies in Latin America.

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