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Gait Disorders and Magnetic Resonance Imaging Characteristics in Older Adults with Cerebral Small Vessel Disease.

J Integr Neurosci · 2022-07-01

DOI: 10.31083/j.jin2105129PMID: 36137968

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Research overview

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BackgroundThis study aims to explore the features of gait disorders with cerebral small vessel disease (CSVD), and results from magnetic resonance imaging (MRI) with diffusion tensor imaging (DTI) were analyzed.MethodsThe 139 patients with CSVD were divided into two groups by the Tinetti scale scores: the gait disorder (GD) group with a score ResultsThe differences in the Barthel Index, Unified Parkinson's Disease Rating Scale part III, and Montreal Cognitive Assessment (MoCA) scores between the two groups were significant (p r = 0.201, p = 0.002). The GD group had a more degraded gait score, widened gait base, and degraded gait length than the GN group (p p p p r = 0.467, p r  = -0.422, p ConclusionsPatients with CSVD with gait disorders had more WMH of Fazekas scale grade 2-3, lacunes, and total MRI burden than the GN patients, and those with gait disorders may suffer from demyelination of nerve fibers and damage to the fibers' microstructures.

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