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Neuroimaging

Explore Parkinson literature by research question and topic.

RESEARCH GUIDE

Find the source. Evaluate the evidence.

This area groups records using publication titles and source-reported publication types. A thematic match is not clinical guidance or expert assessment. Always consult the original study for methods, sample sizes, findings and limitations.

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Method differences in Parkinson neuroimaging

Read the imaging technique, measured signal and research objective together. MRI, functional imaging and nuclear-medicine studies should not be treated as a single method. Even studies using the same technique may differ in populations, devices and analysis procedures. A research classification result alone does not establish an individual diagnostic tool.

Examine acquisition protocols, preprocessing, quality control and comparison groups. For computational models, check independent test data and validation with data from other centers. This topic page supports source discovery; it does not interpret scans or provide personal radiological assessment. Use the original paper to establish what was measured and what the results can support.

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Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.

Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E, Hämmerer D.

Brain · 2019-09-01

DOI: 10.1093/brain/awz193PMID: 31327002

When reading a study

  1. Identify the publication type and research question.
  2. Distinguish human, animal and laboratory research.
  3. Assess results and uncertainty from the original text.
  4. Check the source for retractions and corrections.