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SCIENTIFIC LITERATURE · MED

Neutrophil to lymphocyte ratio in parkinson's disease: a systematic review and meta-analysis.

BMC Neurol · 2023-09-21

DOI: 10.1186/s12883-023-03380-7PMID: 37735638

Open accessMeta-Analysis; research-article; Systematic Review; Journal ArticleOriginal source ↗

Research overview

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BackgroundThe goal of this research was to explore the role of Neutrophil to lymphocyte ratio (NLR) in Parkinson's disease (PD).MethodsFrom inception to 4 June 2023, PubMed, Web of Science, and ProQuest were searched for papers comparing NLR in PD to healthy individuals. Standardized mean difference (SMD) with a confidence interval (CI) of 95% were calculated.ResultsA random-effect model revealed that PD patients had elevated NLR values compared to healthy individuals (SMD = 0.81, 95% CI = 0.47 to 1.14, P ConclusionsIncreased levels of NLR is highly related with the presence of PD. Further research is needed to determine the potential clinical benefits of this simple and low-cost biomarker in the PD diagnosis.

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