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SCIENTIFIC LITERATURE · MED

Roles for primary cilia in synapses and neurological disorders.

Trends Cell Biol · 2024-11-25

DOI: 10.1016/j.tcb.2024.10.014PMID: 39592366

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Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

The role of primary cilia has recently garnered significant attention in the field of neurodegeneration. This review explores the diversity of primary cilia in the mature brain and their interrelationships with a multitude of cellular structures, including axons and synapses. Importantly, an overview of the growing prominence of ciliary-related dysfunctions in neurodegenerative diseases is summarized, with a special emphasis on Parkinson's disease (PD) and neuropsychiatric disorders.

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