NeuralCipher Research overview
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BackgroundWith a progressively aging global population, the prevalence of Parkinson's Disease and dementia will increase, thus multiplying the healthcare burden worldwide. Sensing technology can complement the current measures used for symptom management and monitoring. The aim of this umbrella review is to provide future researchers with a synthesis of the current methodologies and metrics of sensing technologies for the management and monitoring of activities and behavioral symptoms in older adults with neurodegenerative disease. This is of key importance when considering the rapid obsolescence of and potential for future implementation of these technologies into real-world healthcare settings.MethodsSeven medical and technical databases were searched for systematic reviews (2018-2024) that met our inclusion/exclusion criteria. Articles were screened independently using Rayyan. PRISMA guidelines, the Cochrane Handbook for Systematic Reviews, and the Johanna Briggs Institute Critical Appraisal Checklist for Systematic Reviews were utilized for the assessment of bias, quality, and research synthesis. A narrative synthesis combines the study findings.ResultsAfter screening 1458 articles, 9 systematic reviews were eligible for inclusion, synthesizing 402 primary studies. This umbrella review reveals that the use of sensing technologies for the observation and management of activities and behavioral symptoms is promising, however diversely applied, heterogenous in the methods used, and currently challenging to apply within clinical settings.ConclusionsHuman activity and behavioral recognition requires true interdisciplinary collaborations between engineering, data science, and healthcare domains. The standardization of metrics, ethical AI development, and a culture of research-friendly technology and support are the next crucial developments needed for this rising field.
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