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SCIENTIFIC LITERATURE · MED

Striatal Toe: Too Harmless to Treat?

Toxins (Basel) · 2025-04-01

DOI: 10.3390/toxins17040168PMID: 40278665

Open accessreview-article; Review; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

A striatal toe is a misalignment of the hallux in dorsal flexion that frequently presents as a symptom of Parkinson's disease and also atypical Parkinson syndromes. It can negatively impact patients during activities such as walking, putting on socks and shoes, and particularly while wearing shoes. It causes pain and thus induces a loss of quality of life. But, to date, we have few data on the topics of the prevalence, genesis, and therapy of striatal toe. Publications available on botulinum neurotoxin (BoNT) have demonstrated a positive effect in the treatment of striatal toe, although the current study data are also rather limited in this area. Commensurate approval studies have not yet been performed. We will introduce our contemporary data on therapy for striatal toe with BoNT and we will also discuss possible questions open for further study.

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