NeuralCipher Research overview
The text below is the source article’s original abstract under a verified reuse license. cc by
Diosmin and hesperidin, two flavonoid glycosides derived from citrus plants, offer numerous health benefits, whether used alone or in combination. They can mitigate neurodegenerative symptoms and reduce vascular and microbial inflammations, improving cardiovascular health and modulating immunity and anti-oxidant properties. Neuroinflammation and oxidative stress are associated with numerous neurological disorders. This study aims to review the neuroprotective potentials of diosmin and hesperidin, focusing on their effects on oxidative stress and inflammatory conditions. A scientific literature search was conducted using specific keywords in various databases, including PubMed, Web of Science, Google Scholar, Embase, and Scopus.Diosmin and hesperidin demonstrated protective effects in managing a variety of neurological disorders, such as epilepsy, neuropathy, depression, anxiety, insomnia, autism, glioblastoma, traumatic brain injury, cerebral ischemia-reperfusion, Huntington's disease, Alzheimer's disease, Parkinson's disease, neurotoxicity, and multiple sclerosis through the regulation of various signaling pathways. Hesperidin and diosmin exhibit promising neuroprotective effects that underscore their potential as natural multi-targeted therapeutic agents for treating neurological disorders through diverse cascades.
Scientific assessment
Research question
Assess the question within the original study’s scope.
Methods & sample
Check the source article for study design and sample details.
Key findings
An editorially approved findings summary is not yet published for this record.
Limitations
Generalizability, bias and clinical meaning require separate assessment.
Methods, samples and clinical conclusions are not inferred from bibliographic metadata.