SCIENTIFIC HUB

Follow the evidence.

SCIENTIFIC LITERATURE · MED

Correlation between gait parameters and clinical scales in individuals with Parkinson's disease.

Dement Neuropsychol · 2025-09-05

DOI: 10.1590/1980-5764-dn-2024-0205PMID: 40959465

Open accessresearch-article; Journal ArticleOriginal source ↗

Research overview

The text below is the source article’s original abstract under a verified reuse license. cc by

The ability to walk independently is essential for the quality of life of individuals with Parkinson's disease (PD), and aspects such as mobility, balance, and cognition are important for walking. However, the association between these factors has not yet been fully established.ObjectiveTo verify the correlations between cognitive and motor clinical scales, and gait intervals in individuals with PD.MethodsTwenty-two individuals with a clinical diagnosis of idiopathic PD were evaluated using balance and cognitive tests to classify the severity of the disease and gait analysis in the laboratory.ResultsThe Unified Parkinson's Disease Rating Scale, motor part (UPDRS-III) was directly related to step width in the OFF state of medication (p=0.029); the Mini-Test of Balance Assessment System (Mini-BESTest) was inversely proportional to step width in medication ON (p=0.001) and OFF (p=0.005) states; Stroop-III was directly proportional to the stride time (p=0.039) and the stance (p=0.003) and double stance (p=0.011) phases and inversely proportional to the cadence (p=0.033) and swing phase (p=0.003), both in the ON state of medication; the Trail Making Test Part A (TMTB-A) was inversely proportional to step size (p=0.035), stride size (p=0.037), cadence (p=0.036) and speed (p=0.003) in the ON state.ConclusionCognitive dysfunctions are directly related to gait instability in PD, reinforcing the importance of interventions that integrate motor and cognitive rehabilitation. These strategies can improve gait safety and efficacy in individuals with PD.

Scientific assessment

01

Research question

Assess the question within the original study’s scope.

02

Methods & sample

Check the source article for study design and sample details.

03

Key findings

An editorially approved findings summary is not yet published for this record.

04

Limitations

Generalizability, bias and clinical meaning require separate assessment.

Methods, samples and clinical conclusions are not inferred from bibliographic metadata.