Research overview
The text below is the source article’s original abstract under a verified reuse license. cc by
IntroductionParkinson's disease (PD) is characterized not only by motor symptoms but also by non-motor impairments, including deficits in social cognition (SC), defined as the ability to recognize, interpret, and respond to others' emotions, intentions, and behaviors. This systematic review synthesizes evidence on SC in PD, focusing on three core aspects: emotion recognition, empathy/Theory of Mind (ToM), and social problem-solving.MethodsWe included 191 behavioral and neuroimaging studies based on a PRISMA-guided search of four databases.ResultsThe literature review findings revealed relatively consistent impairments in the recognition of negative emotions, such as fear and anger, and heterogeneous findings for empathy/ToM, with deficits being more pronounced in advanced PD or in patients with mild cognitive impairment (MCI). Social problem-solving remains understudied, though emerging evidence links it to dopaminergic modulation.DiscussionAcross all three aspects, methodological heterogeneity and the scarcity of neuroimaging studies addressing complex SC aspects underscore the need for standardized, multimodal research. Beyond synthesizing the literature, we propose an integrative neurofunctional model of SC in PD that emphasizes its componential nature and highlights the need for future studies to clarify interrelations among SC domains and their neural substrates.
Scientific assessment
Research question
Assess the question within the original study’s scope.
Methods & sample
Check the source article for study design and sample details.
Key findings
An editorially approved findings summary is not yet published for this record.
Limitations
Generalizability, bias and clinical meaning require separate assessment.
Methods, samples and clinical conclusions are not inferred from bibliographic metadata.