NeuralCipher Research overview
The text below is the source article’s original abstract under a verified reuse license. cc by
In this datanote we presented the data of 31 iRBD (idiopathic Rapid eye movement (REM) sleep Behaviour Disorder) patients studied throughout three years to assess their eventual phenoconversion to Parkinson’s disease and other established neurodegenerative conditions. iRBD is a prodromal condition involved in the development of neurological pathologies such as Parkinson’s disease. In a previous study we evaluated transcription factor mRNA levels in CD4+ T cells as predictive biomarkers of phenoconversion in iRBD. We demonstrated that among the transcription factors mRNA levels analysed, STAT1, GATA3 and FOXP3 mRNA levels in CD4+ T cells may be used to predict phenoconversion.
Scientific assessment
Research question
Assess the question within the original study’s scope.
Methods & sample
Check the source article for study design and sample details.
Key findings
An editorially approved findings summary is not yet published for this record.
Limitations
Generalizability, bias and clinical meaning require separate assessment.
Methods, samples and clinical conclusions are not inferred from bibliographic metadata.