Research overview
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Optimal subthalamic nucleus deep-brain stimulation (STN-DBS) for Parkinson's disease reduces motor symptoms without stimulating adjacent structures and causing side-effects. Fine-tuning STN-DBS using clinical evaluation is time-consuming and often requires multiple follow-ups. Electrophysiological recordings may enhance STN-DBS device programming for clinicians by providing objective evidence of neural pathway activation. This literature review critically evaluates evoked potentials as biomarkers of optimal STN-DBS and assesses potential integration into the device programming toolkit.
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